Tip W. Loo : rechercher sur Z-Library

Expert Reviews in Molecular Medicine

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 692 KB

english, 2007

Expression and mutation of Ca2+ ATPases of the sarcoplasmic reticulum

Kei Maruyama, David M. Clarke, Junichi Fujii, Tip W. Loo, Dr. David H. MacLennan

Journal:

Cytoskeleton

Année:

1989

Langue:

english

Fichier:

PDF, 958 KB

english, 1989

Rescue of Folding Defects in ABC Transporters Using Pharmacological Chaperones

Tip W. Loo, M. Claire Bartlett, David M. Clarke

Journal:

Journal of Bioenergetics and Biomembranes

Année:

2005

Langue:

english

Fichier:

PDF, 203 KB

english, 2005

Location of high affinity Ca2 +-binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca2+-ATPase

Clarke, David M., Loo, Tip W., Inesi, Giuseppe, MacLennan, David H.

Journal:

Nature

Année:

1989

Fichier:

PDF, 397 KB

1989

Using a cysteine-less mutant to provide insight into the structure and mechanism of CFTR

The Journal of Physiology

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 46 KB

english, 2006

Cystic Fibrosis: Channel, Catalytic, and Folding Properties of the CFTR Protein

Fabian S. Seibert, Tip W. Loo, David M. Clarke, John R. Riordan

Journal:

Journal of Bioenergetics and Biomembranes

Année:

1997

Langue:

english

Fichier:

PDF, 1.48 MB

english, 1997

Chalcogenopyrylium Compounds as Modulators of the ATP-Binding Cassette Transporters P-Glycoprotein (P-gp/ ABCB1 ) and Multidrug Resistance Protein 1 (MRP1/ ABCC1 )

Ebert, Sean P., Wetzel, Bryan, Myette, Robert L., Conseil, Gwenaëlle, Cole, Susan P. C., Sawada, Geri A., Loo, Tip W., Bartlett, M. Claire, Clarke, David M., Detty, Michael R.

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2012

Corrector-mediated rescue of misprocessed CFTR mutants can be reduced by the P-glycoprotein drug pump

Tip W. Loo, M. Claire Bartlett, Li Shi, David M. Clarke

Journal:

David M. CLARKE, Tip W. LOO, Shirley GILLAM, Philip D. BRAGG

Année:

2012

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2012

Nucleotide sequence of the pntA and pntB genes encoding the pyridine nucleotide transhydrogenase of Escherichia coli

Journal:

FEBS Journal

Année:

1986

Langue:

english

Fichier:

PDF, 577 KB

english, 1986

Nonylphenol Ethoxylates, but Not Nonylphenol, Are Substrates of the Human Multidrug Resistance P-glycoprotein

Biochemical and Biophysical Research Communications

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 97 KB

english, 1998

Interaction of Escherichia coli F1-ATPase with dicyclohexylcarbodiimide-binding polypeptide

Tip W. Loo, Helga Stan-Lotter, Donald Mackenzie, Robert S. Molday, Philip D. Bragg

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1983

Langue:

english

Fichier:

PDF, 649 KB

english, 1983

The DCCD-binding polypeptide is close to the F1 ATPase-binding site on the cytoplasmic surface of the cell membrane of Escherichia coli

Tip W. Loo, P.D. Bragg

Journal:

Biochemical and Biophysical Research Communications

Année:

1982

Langue:

english

Fichier:

PDF, 365 KB

english, 1982

Structural analysis of a new GC-specific insertion element IS186

Pele Chong, Ivy Hui, Tip Loo, Shirley Gillam

Journal:

FEBS Letters

Année:

1985

Langue:

english

Fichier:

PDF, 490 KB

english, 1985

Deletion of NH2− and COOH-terminal sequences destroys function of the Ca2+ ATPase of rabbit fast-twitch skeletal muscle sarcoplasmic reticulum

Ilona S. Skerjanc, David M. Clarke, Tip W. Loo, David H. MacLennan

Journal:

FEBS Letters

Année:

1993

Langue:

english

Fichier:

PDF, 415 KB

english, 1993

Mutational analysis of ABC proteins

Archives of Biochemistry and Biophysics

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 716 KB

english, 2008

Thapsigargin or curcumin does not promote maturation of processing mutants of the ABC transporters, CFTR, and P-glycoprotein

Tip W. Loo, M. Claire Bartlett, David M. Clarke

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 447 KB

english, 2004

Do drug substrates enter the common drug-binding pocket of P-glycoprotein through “gates”?

Biochemical and Biophysical Research Communications

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 490 KB

english, 2005

Human P-glycoprotein is active when the two halves are clamped together in the closed conformation

Tip W. Loo, M. Claire Bartlett, David M. Clarke

Journal:

Biochemical and Biophysical Research Communications

Année:

2010

Langue:

english

Fichier:

PDF, 639 KB

english, 2010

Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1)

Alexandra Orchard, Gregory A. Schamerhorn, Brandon D. Calitree, Geri A. Sawada, Tip W. Loo, M. Claire Bartlett, David M. Clarke, Michael R. Detty

Journal:

Bioorganic & Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 934 KB

english, 2012

Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques

Biochimica et Biophysica Acta (BBA) - Biomembranes

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 510 KB

english, 1999

Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 457 KB

english, 2006

Transmembrane segment 7 of human P-glycoprotein forms part of the drug-binding pocket

Loo, Tip W, Clarke, David M

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 494 KB

english, 2006

Molecular dissection of the human multidrug resistance P-glycoprotein

Journal:

Biochemistry and Cell Biology

Année:

1999

Langue:

english

Fichier:

PDF, 265 KB

english, 1999

The DCCD-binding polypeptide alone is insufficient for proton translocation through F0 in membranes of Escherichia, coli

Tip W. Loo, P.D. Bragg

Journal:

Biochemical and Biophysical Research Communications

Année:

1981

Langue:

english

Fichier:

PDF, 1.73 MB

english, 1981

Detection of antibodies to individual proteins of rubella virus

Tip W. Loo, Ian Macdonald, David M. Clarke, Michel Trudel, Aubrey Tingle, Shirley Gilam

Journal:

Journal of Virological Methods

Année:

1986

Langue:

english

Fichier:

PDF, 616 KB

english, 1986

ATP Hydrolysis Promotes Interactions between the Extracellular Ends of Transmembrane Segments 1 and 11 of Human Multidrug Resistance P-Glycoprotein †

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 425 KB

english, 2005

A Salt Bridge in Intracellular Loop 2 Is Essential for Folding of Human P-Glycoprotein

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 724 KB

english, 2013

Niemann-Pick NPC1: Sterols to the Rescue and Beyond

Journal:

Chemistry & Biology

Année:

2013

Langue:

english

Fichier:

PDF, 170 KB

english, 2013

Corrector VX-809 stabilizes the first transmembrane domain of CFTR

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2013

Nucleotide sequence and in vitro expression of rubella virus 24S subgenomic messenger RNA encoding the structural proteins E 1 , E 2 , and C

Clarke, David M., Loo, Tip W., Hui, Ivy, Chong, Pele, Gillam, Shirley

Journal:

Nucleic Acids Research

Année:

1987

Langue:

english

Fichier:

PDF, 1.65 MB

english, 1987

Disease-Associated Mutations in Cytoplasmic Loops 1 and 2 of Cystic Fibrosis Transmembrane Conductance Regulator Impede Processing or Opening of the Channel †

Seibert, Fabian S., Jia, Yanlin, Mathews, Ceri J., Hanrahan, John W., Riordan, John R., Loo, Tip W., Clarke, David M.

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 596 KB

english, 1997

Nucleotide Binding, ATP Hydrolysis, and Mutation of the Catalytic Carboxylates of Human P-Glycoprotein Cause Distinct Conformational Changes in the Transmembrane Segments †

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 311 KB

english, 2007

The cystic fibrosis V232D mutation inhibits CFTR maturation by disrupting a hydrophobic pocket rather than formation of aberrant interhelical hydrogen bonds

Journal:

Clarke, David M., Loo, Tip W., McDonald, Helen, Gillam, Shirley

Année:

2014

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2014

Expression of rubella virus cDNA coding for the structural proteins

Journal:

Gene

Année:

1988

Langue:

english

Fichier:

PDF, 912 KB

english, 1988

The Drug-Binding Pocket of the Human Multidrug Resistance P-Glycoprotein Is Accessible to the Aqueous Medium †

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 165 KB

english, 2004

The W232R Suppressor Mutation Promotes Maturation of a Truncation Mutant Lacking both Nucleotide-Binding Domains and Restores Interdomain Assembly and Activity of P-glycoprotein Processing Mutants

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.72 MB

english, 2011

Disulfiram Metabolites Permanently Inactivate the Human Multidrug Resistance P-Glycoprotein †

Journal:

Molecular Pharmaceutics

Année:

2004

Langue:

english

Fichier:

PDF, 220 KB

english, 2004

The V510D Suppressor Mutation Stabilizes ΔF508-CFTR at the Cell Surface

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 2.61 MB

english, 2010

Correctors Enhance Maturation of ΔF508 CFTR by Promoting Interactions between the Two Halves of the Molecule

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 3.26 MB

english, 2009

The Glycosylation and Orientation in the Membrane of the Third Cytoplasmic Loop of Human P-Glycoprotein Is Affected by Mutations and Substrates †

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 109 KB

english, 1999

Benzbromarone Stabilizes ΔF508 CFTR at the Cell Surface

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 979 KB

english, 2011

Drug Rescue Distinguishes between Different Structural Models of Human P-Glycoprotein

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 1023 KB

english, 2013

Bithiazole Correctors Rescue CFTR Mutants by Two Different Mechanisms

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 979 KB

english, 2013

Rescue of ΔF508 and Other Misprocessed CFTR Mutants by a Novel Quinazoline Compound †

Journal:

Molecular Pharmaceutics

Année:

2005

Langue:

english

Fichier:

PDF, 168 KB

english, 2005

Mutations to Amino Acids Located in Predicted Transmembrane Segment 6 (TM6) Modulate the Activity and Substrate Specificity of Human P-glycoprotein

Journal:

Gannon, Michael K., Holt, Jason J., Bennett, Stephanie M., Wetzel, Bryan R., Loo, Tip W., Bartlett, M. Claire, Clarke, David M., Sawada, Geri A., Higgins, J. William, Tombline, Gregory, Raub, Thomas J

Année:

1994

Langue:

english

Fichier:

PDF, 2.71 MB

english, 1994

Rhodamine Inhibitors of P-Glycoprotein: An Amide/Thioamide “Switch” for ATPase Activity

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 302 KB

english, 2009

Tariquidar inhibits P-glycoprotein drug efflux but activates ATPase activity by blocking transition to an open conformation

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 962 KB

english, 2014

Insertion of an Arginine Residue into the Transmembrane Segments Corrects Protein Misfolding

Journal of Biological Chemistry

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 721 KB

english, 2006

The Transmission Interfaces Contribute Asymmetrically to the Assembly and Activity of Human P-glycoprotein

Journal of Biological Chemistry

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2015

Mapping the Binding Site of the Inhibitor Tariquidar That Stabilizes the First Transmembrane Domain of P-glycoprotein